Songs are presented in the table below with the year they were recorded (based on the in-game description), song title, and artist, and the placement of the song in the band career mode. The set list has been described as containing well-known songs by 'an impressive collection of artists' such as Van Halen, Jimi Hendrix, Joe Satriani, and Tool, as well as a considerable number of tracks from European bands.

Once a player or band has access to a song via any instrument or band Career mode, that song can be played in Quickplay mode or any of the other competitive modes in the game. The player or band must complete easier gigs before the more difficult gigs are available.

These gigs are arranged approximately based on the difficulty of the songs in that gig for the selected instrument or band, with more difficult songs appearing in later gigs. In the single player and multiplayer band (Career Mode) modes, songs are distributed into various 'gigs' that contain between 3 and 6 songs each gigs may also contain a boss battle (for the single player guitar career) and encores that are revealed once all the other songs in the gig are completed. The game disc contains 86 songs, all of which are master recordings-a first for the Guitar Hero series. A new music creation system also allows users on the same systems to gain new user-created songs through the game's 'GHTunes' service. In addition to the on-disk songs, the PlayStation 3, Xbox 360, and Wii versions support the ability to obtain new songs through downloadable content. For each instrument, the player scores points by matching controller actions with note gems on the game screen to avoid a bad performance that may end the song prematurely. While previous versions of the series have only used a guitar-based controller for lead and bass guitar tracks, World Tour adds in drums and vocals, allowing up to four players to create a virtual band. Guitar Hero World Tour, like the other games in the Guitar Hero series, focuses on the use of special game controllers to mimic musical tracks from popular rock songs that date from the 1960s to contemporary hits. The game was developed by Neversoft, with assistance from Vicarious Visions and Budcat Creations for the Wii and PlayStation 2 versions, respectively, and distributed by RedOctane and Activision. It was released in Europe and on a limited basis in North America for the Microsoft Windows and AppleMacintosh platforms. The game was released in October 2008 for the PlayStation 2, PlayStation 3, Wii, and Xbox 360 game consoles in North America, and a month later for PAL regions. Guitar Hero World Tour is the fourth major release in the Guitar Hero series of musicvideo games, a series that has sold over 24 million units and earned more than $1.6 billion in retail sales.

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